As most of you know, I'm a big twitter user (not a big twit) and now I also have a Wii. I think it would be cool of there was a bridge made that could tell twitter what I've recently done on my Wii? and for that matter, maybe on my 360 as well. I'm guessing for the 360 it would be pretty easy since what you have done on your 360 is pretty much public information via XBox Live API, but I think the Wii will be considerably more difficult :(
Give it a shot, happy hacking and report back here if you find something please!